When a raid in Manila's most dangerous slum goes wrong, leaving an elite anti-drug squad trapped between a brutal cartel and hordes of blood thirsty civilians, their only option is to fight their way out, turning each street into asymphony of apocalyptic violence.

The film follows Rosa and her husband Nestor, owners of a tiny convenience store who supplement their meager income by selling small amounts of 'ice' (crystal meth). Eventually the couple gets caught and hauled away by police, who are more interested in collecting bribes than eradicating crime. With their parents locked away, it's left to Rosa's children to scrounge together the money to pay off the police and free their parents, by any means necessary....

After 30 years in prison, Horcia discovers that her friend and fellow inmate committed the murder of which she was accused. This leads to her release and the transformative discovery of the man who framed her.