Banned in it's home country of Cuba, SANTA & ANDRES is the story of an improbable friendship between a revolutionary country girl and a noncompliant gay writer.

Matias and Jeronimo, childhood friends, before starting high school they both experience their sexual awakening and their friendship takes a new turn. Matias's father breaks their relationship up by accepting a job far away. Ten years later, Matias returns to his old town for carnival with his girlfriend and unexpectedly runs in Jeronimo. Fellings slowly start to reappear and reach a climax, but at what price?

It tells of a series of reencounters experienced by Salvador Mallo, a film director in his physical decline. Some of them in the flesh, others remembered: his childhood in the '60s, when he emigrated with his parents to a village in Valencia in search of prosperity, the first desire, his first adult love in the Madrid of the '80s, the pain of the breakup of that love while it was still alive and intense.