After their mother dies of typhoid, Verna and her younger sister Carlie move with their father, a psychiatrist, and stern Aunt Maude to an asylum for the mentally ill in early-twentieth-century Michigan, where new ideas in the treatment of mental illness are being proposed, but old prejudices still hold sway.

When Andy and his friend Tamika spend the weekend in the city with Tamika's aunt and uncle, he tries hard to follow all the rules of etiquette during outings to a French restaurant, an art museum, and the ballet, while using his detective skills to solve a mystery involving parachuting hamsters.

After their mother abandons them during the Great Depression, eleven-year-old Tennyson Fontaine and her little sister Hattie are sent to live with their eccentric Aunt Henrietta in a decaying plantation house outside of New Orleans.

In 1938, Edith Westerfeld, a young German Jew, is sent by her parents to Chicago, Illinois, where she lives with an aunt and uncle and tries to assimilate into American culture, while worrying about her parents and mourning the loss of everything she has ever known. Based on the author's mother's experience, includes an afterword about a little-known program that brought twelve hundred Jewish children to safety during World War II.